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Also referred as Chinese corktree, phellodendron, phellodendron-bark, phellodendron, Amur corktree, Huang Bai, cortex Phellodendri, nark of Chinese corktree, phellodendron bark, cortex phellodendri Chinensis, Amur corktree bark, Amur cork bark, Japanese corktree, this tree species belongs to the family Rutaceae. The tree typically grows up to the height of 30-60′. The trunk is 1-3′ across with gray outer bark that is furrowed and has rough texture and inner bark is bright yellow, soft and corky. The green leaves are 10-15 inches in length that is pinnately compound and opposite. The leaflets are 2½-5″ long, 1-1¾” in across, lanceolate to ovate, broadly elliptic having smooth and ciliate margins. The glabrous and pubescent branches are light green to yellowish green. The tree bears yellowish to green flowers which turns to a green or black fruit of oval shape with ¼-½ inch in diameter. It has stout, light to yellow gray twigs. This deciduous plant requires full sun and rich soils. This herb contains limonin, alkaloids, obacunonic acid, obacunone, β-sitosterol, 7-dehydrostigmasterol, campesterol. It possess the alkaloids such as phellodendrine, berberine, jatrorrhizine, magnoflorine and palmatine.
History
Inherent to Eastern Asia that includes Japan, Korea, Northern China (Ussuri, Manchuria, Amur). It got introduced for ornamental purposes in United States in 1856. It has been intrusive in Maryland, Illinois, New York, Virginia and Pennsylvania.
This tree got introduced around 1856 in U.D. Firstly the sachalinense variety was acquired by Havard University Arnold Arboretum in 1901 and in 1906, the true amurense. In 1933, it was reported by New York Botanical Garden to be naturalized in forests where it is found today. The bark is used in China, Japan and India for traditional medicines. In ancient China, the inner yellow bark is used to make special dye and yellow paper for the religious and governmental documents. It is used as street tree or ornamental purposes so its demand is increasing as shown by the study in Ohio of urban foresters. The wood is used for manufacturing railings as well as bollards for the erosion control.
Health Benefits of Amur Cork Tree
This herb is used for treating bacillary dysentery, cerebrospinal meningitis, tuberculosis, pneumonia, chronic hepatitis, liver cirrhosis, acute conjunctivitis, trichomoniasis vaginitis, cervical spondylosis, chronic suppurative otitis media and ear eczema.
- Lowers chances of prostate cancer
The study shows that the diet based on plants lowers the chances of prostate cancer. The effect of Nexrutine was examined which an herbal extract is made from Phellodendron amurense which is traditionally used in Chinese medicine for about hundred years for its astringent, anti-diarrheal and anti-inflammatory properties. It inhibits the proliferation of tumor cells by induction of apoptosis and also inhibits the signaling of cell survival. The results shows that the treatment of Nexrutine inhibit proliferation of androgen independent and androgen responsive human prostate cancer cells with apoptosis induction.
- Treatment for osteoporosis
Phellodendron amursense, Cinnamomum cassia and Astragalus membranaceus was used traditionally for the treatment of inflammatory diseases and osteoporosis. It raised the mineral density of bones and prevents decrease of trabecular bone volume, trabecular number, connectivity density, thickness, trabecular number and separation at femur neck and total femur. The serum levels of phosphorus and calcium was decreased in OVX rats and increase in low density lipoprotein, cholesterol, osteocalcin, phosphatase, bone morphogenetic protein-2 and C-telopeptide type 1 collagen. The results shows that BHH10 has the ability to reverse osteoporosis in OVX rats as it stimulates the formation of bones and regulates bone resorption and as it is not related with toxicity.
- Memory dysfunction
The study in the improvement of memory defects caused due to administering scopolamine with the use of Phellodendron amurense and berberine. The effects of BER and PA were found on pro-inflammatory cytokines and acetylcholinergic system. The male rats were provided a daily dose of 100 or 200 mg /kg of PA for 14 days and BER of 20 mg/kg 30 minutes before scopolamine injection. It improved impairment of memory. It alleviated cholinergic immunoreactivity and also restored brain derived neurotrophic factor. It has neuroprotective effects on memory dysfunction and neuronal impairment. It stimulates cholinergic enzyme activity and alleviates inflammatory responses that helsp to improve cognitive functioning.
- Lowers anxiety and stress
The medicinal plants such as Phellodendron and Magnolia are used as traditional remedies for lowering anxiety and stress. The modern dietary supplements promote relaxation and promote stress and also stress related eating. The studies show that is combination lowers perception of anxiety as well as stress and cortisol exposure that improves weight loss.
Traditional uses
- The remedy made from bark acts as a detoxicant.
- It is used to treat conjunctivitis and meningitis.
- Its internal use helps to treat dysentery, acute diarrhea, vaginal infections, jaundice, enteritis, urinary tract infections, abscesses, boils, skin diseases and night sweats.
- The preparation named “injection of three yellow herbs” is made with Coptis chinensis and Scutellaria baicalensis that is useful for upper respiratory tract infections.
- Ainu people use this plant as a pain killer.
- It is used as a treatment for pneumonia, bacillary dysentery, meningitis, liver cirrhosis and tuberculosis.
- The oil is used to treat pancreatitis, lowers cholesterol and sugar in blood and also treats skin ailments.
- Traditionally, it is used to reduce fever.
- The fruit is helpful for treating the cold symptoms.
- Externally it is used to treat eczema around ears.
- It is an aid for meningitis and used as an eyewash for conjunctivitis.
- It lowers fever, blood pressure, blood sugar level and also treat kidney and urine problems.
Precautions
- Pregnant women should not use it.
- Not to be used by the people with weak or cold stomach and spleen conditions.
- Use with professional advice.
Other Facts
Due to illegal and excessive harvesting, the population has declined.
Amur Cork Tree facts
Amur Cork tree is the tree of medium sized having a corky bark and is pest free. It is a deciduous tree that has gray outer bark having thick cork layer with its longitudinal fissure surface and bright yellow under bark. The massive branches spread widely. The branchlets are mostly brown to light brown but rarely found red to orange. It has small and indistinctive flowers which could be either female or male. It has unisexual flowers that are small and dioecious. It is native to Asia and was introduced for its ornamental qualities.
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Phellodendron appears to be safe in adults when used short-term. The safety of phellodendron use for more than 6 weeks is unknown. In one study, one person experienced heartburn, shaking hands, sexual dysfunction, and thyroid dysfunction. Another person experienced fatigue and headache. But it is not known if these side effects were caused by phellodendron or some other factor.
Special Precautions & Warnings:
Pregnancy and breast-feeding: It's UNSAFE to use phellodendron if you are pregnant. Phellodendron contains a chemical called berberine, which can cross the placenta and might harm the fetus. It's also UNSAFE to use phellodendron if you are breast-feeding. Berberine can be transferred to the infant through breast milk and can cause brain damage in newborns, especially in premature newborns with jaundice. Jaundice is a yellowing of the eyes and skin due to bile pigments in the blood.
Children: Phellodendron is UNSAFE in newborn infants. It can cause brain damage, especially in premature infants with jaundice.
Interactions
Cyclosporine (Neoral, Sandimmune)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
The body breaks down cyclosporine (Neoral, Sandimmune) to get rid of it. Phellodendron might decrease how fast the body breaks down cyclosporine (Neoral, Sandimmune). Taking phellodendron along with cyclosporine (Neoral, Sandimmune) might increase the chance of side effects.
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Some medications are changed and broken down by the liver. Phellodendron might decrease how quickly the liver breaks down some medications. Taking phellodendron along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking phellodendron, talk to your healthcare provider if you are taking any medications that are changed by the liver.
Some medications changed by the liver include cyclosporine (Neoral, Sandimmune), lovastatin (Mevacor), clarithromycin (Biaxin), indinavir (Crixivan), sildenafil (Viagra), triazolam (Halcion), and many others. *