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Witch hazel is relatively safe.
Side effects. Stomach upset may result from taking witch hazel by mouth. When you apply it to skin, it may, rarely, cause inflammation (contact dermatitis). But even children tend to tolerate it well on the skin.
Risks. If you use witch hazel in appropriate amounts, your risks are relatively minor. But if you take high doses by mouth, it may cause kidney or liver damage.
Although witch hazel contains a known cancer-causing ingredient, there's likely no need for concern unless you regularly use high concentrations. The amounts are very small.
Because studies are limited, avoid using witch hazel if you are pregnant or breastfeeding.
Interactions. There aren't any known interactions with drugs, foods, or other herbs and supplements. *