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There are not many noted negative effects which arise from Lion’s Mane supplementation.
The majority of users that experience negative effects report a experience of scratchy skin which can be explained by a boost in Nerve Growth Factor. Unless accompanied by other allergy-like signs, this really is likely the cause and may even actually be a sign that the Lion’s Mane is growing your NGF levels.
Lion’s Mane have been examined in mice and it has demonstrated no indications of poisoning even up to 5 g/kg and is also therefore regarded as safe. It is still suggested to supplement in the suggested dosages. *