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When taken by mouth: Guggul is
POSSIBLY SAFE for most people when taken appropriately. It has been used safely for up to 24 weeks. Some research also suggests that long-term use up to 75 weeks may be safe.
When taken by mouth, guggul may cause stomach upset, headaches, nausea, vomiting, loose stools, diarrhea, belching, and hiccups. Guggul may also cause allergic reactions such as rash and itching. Guggul can also cause skin rash and itching that is not related to allergy. These adverse reactions are more common with higher doses, such as 6 grams per day.
Pregnancy: Guggul is LIKELY UNSAFE during pregnancy. It seems to encourage menstrual flow and stimulate the uterus. Some researchers worry that this might cause a miscarriage or early labor. Avoid using.
Breast-feeding: There isn't enough reliable information to know if guggul is safe to use when breast-feeding. Stay on the safe side and avoid use.
Bleeding disorders: Guggul can slow blood clotting and might cause bleeding or bruising in people with bleeding disorders.
High cholesterol: Guggul might increase levels of low-density lipoprotein (LDL or "bad") cholesterol in some people with high cholesterol levels.
Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Guggul might act like estrogen in the body. If you have any condition that might be made worse by exposure to estrogen, do not use guggul.
Surgery: Guggul might increase the risk of bleeding during and after surgery. Stop using guggul at least 2 weeks before a scheduled surgery.
Underactive or overactive thyroid hypothyroidism or hyperthyroidism): Guggul might interfere with treatment for these conditions. If you have a thyroid condition, don't use guggul without your healthcare provider's supervision. *