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Side effects of fucoidan are dependent on the type of extract as well as the consumer. Those who are already taking blood-thinning medications, for example, may be more prone to symptoms like lightheadedness and bruising, given that most types of fucoidan have anticoagulant properties. On the other hand, a fucoidan extract from mozuku seaweed actually has a blood-thickening effect. Thus, it is important to research from which product the fucoidan is being extracted before consumption. Additionally, some fucoidan extracts contain xylose or mannose, which are monosaccharide sugars that can cause diarrhea.
Fucoidan possesses high amounts of iodine. Since the human body rapidly excretes excessive iodine, consumption of seaweed a few times a week or ingestion of fucoidan supplements at the recommended dosage should not present a problem. However, those with sensitivities to iodine or sodium should consult a doctor before starting any sort of health regimen based on seaweed or its extracts. Pregnant and lactating women should not exceed a supplemental dosage of 150 mcg of iodine a day. Individuals with hyperthyroidism should also be cautious, as most endocrinologists would advise against the consumption of high-iodine supplements in conjunction with this condition.
There is some correlation between soy, mushroom, and fucoidan allergies, so those who react negatively to these products should consult a physician before consuming large amounts of brown seaweed or fucoidan extracts. *