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High levels of intravenous folic acid intake may cause seizures, and high doses of supplemental folic acid have been associated with an increased risk of the progression of certain cancers.
Dietary levels of folate have not, however, been associated with any adverse effects.
An intake of folate above 1000 mcg for adults or 800 mcg for those aged 18 years or under can hide a deficiency of vitamin B12. Vitamin B12 deficiency can cause permanent nerve damage and paralysis.
Folate is only beneficial as part of a wide-ranging, varied, and nutritious diet. *