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Safety
Beta-sitosterol is likely safe when taken orally for up to 18 months; it may also be safe when applied topically for up to 20 days.
There is insufficient information on the overall safety of beta-sitosterol for pregnant and breastfeeding women; best to avoid.
Children may safely use beta-sitosterol for medicinal purposes under the supervision of a physician.
Beta-sitosterol is generally well-tolerated although some side effects may include the following:
- • Gas
- • Indigestion
- • Diarrhea
- • Reduced appetite
- • Constipation
- • Exacerbation of acne
- • Loss of libido
- • Erectile dysfunction
Medication Interactions
Ezetimibe inhibits intestinal absorption of beta-sitosterol and reduces plasma concentrations in people with and without sitosterolemia. Pravastatin can also lower blood levels of beta-sitosterol.
Supplement and Food Interactions
Beta-sitosterol might reduce the absorption and blood levels of alpha-carotene, beta-carotene, and vitamin E in herbs, supplements, and foods. *