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The following doses have been studied in scientific research:
ADULTS
BY MOUTH:
- General: There is no recommended dietary allowance (RDA) established for biotin. The adequate intakes (AI) for biotin are 30 mcg for adults over 18 years and pregnant women, and 35 mcg for breast-feeding women.
- Biotin deficiency: Up to 10 mg daily has been used.
CHILDREN
BY MOUTH:
- General: There is no recommended dietary allowance (RDA) established for biotin. The adequate intakes (AI) for biotin are 7 mcg for infants 0-12 months, 8 mcg for children 1-3 years, 12 mcg for children 4-8 years, 20 mcg for children 9-13 years, and 25 mcg for adolescents 14-18 years.
- Biotin deficiency: Up to 10 mg daily has been used in infants. *
The only known supplemental dose of biotin that has been tested orally in humans — for the purposes of enhancing the quality of brittle nails — is 2.5 mg taken once daily over six months.
This dose appears relatively safe, although it is much higher than the recommended daily intake (RDI) of biotin which ranges from 25-30 mcg (youth) upwards to 100 mcg (adults). The biotin dose found in many multivitamins (30 mcg or 0.03 mg) seems more than sufficient. *
