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Dosing for digestive enzyme supplements differs for each enzyme and different conditions. The following has been suggested:
- Bromelain: Up to 400 milligrams (mg) per day by mouth
- Chymotrypsin: Up to 100,000 USP four times daily by mouth
- Papain: Up to 1,500 milligrams per day by mouth
- Trypsin: Up to 50 milligrams, combined with bromelain
Digestive enzymes are usually taken before meals.
As a general rule, never take more than the recommended dose. Follow instructions on product labels and include your healthcare provider and pharmacist in your decisions.*