https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712861/
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Nothing Boring About Boron
Boron significantly improves magnesium absorption and deposition in bone, yet another beneficial effect of boron’s inhibition of 17β-estradiol degradation. Thus, boron is a factor in magnesium’s myriad beneficial effects. Magnesium’s importance, in bone alone, is illustrative of the widespread ramifications of boron insufficiency.
Approximately 60% of the magnesium in the human body is found in bone, where it is a cofactor for key enzymes that regulate calcium metabolism. The majority of magnesium in bone resides on cortical bone, an integral part of the structure of apatite crystal. Apart from its structural role in apatite crystals, magnesium is required in osteoblasts and osteoclasts and in all living cells, within which magnesium is fundamental for adenosine triphosphate (ATP) production and serves as the cofactor of more than 300 enzymes involved in lipid, protein, and nucleic acid synthesis. Because of its positive charge, magnesium stabilizes cell membranes, balances the actions of calcium, and functions as a signal transducer.
