Abstract
Four new sesquiterpenoids named atrchiterpene A-D ( 1 - 4 ), a new natural product ( 5 ), and twelve known compounds ( 6 - 17 ) were isolated from Atractylodes chinensis (DC.) Koidz. Compound 1 was a rare N-containing eudesmane-type sesquiterpenoid. The spectroscopic techniques performed structure elucidation, including 1D, 2D NMR spectra, and HRESIMS. Compounds 6 - 11 , 14 , and 17 were reported from Atractylodes for the first time. All compounds were evaluated for their cytotoxic activity against HepG2 (human liver cancer) cancer cell line. Compound 16 showed a significant inhibitory effect on HepG2 cells with an IC 50 value of 5.81 ± 0.47.
Full text
