Abstract
Whey protein is a popular dietary product that has numerous health benefits such as immune modulation. In this study, we assessed efficacy of whey protein in management of patients with contact dermatitis through a double blind, randomized controlled clinical trial in Emam Reza clinic, Shiraz, Iran. Twenty-five patients in each group were randomly assigned to receive whey protein or placebo powder, 30 gr in 200 cc warm water at fasting time for four weeks. Outcome measures were Dermatology Life Quality Index (DLQI) questionnaire and the Eczema Area and Severity Index (EASI) score. Furthermore, subjective total improvement (assessed by visual analogue scale) was set as the other primary outcome measure. A significant decrease was observed in the scores of EASI, DLQI and subjective total improvement in the drug group after the intervention compared to the baseline. However, no changes were seen in the placebo group. Moreover, there was a significant reduction in the scores of EASI (p=0.002) and subjective total improvement scores (p=0.039) over the study period in the drug group compared with the placebo group. According to the results of this study, it seems that oral supplementation of whey protein could improve the symptoms of contact dermatitis compared to placebo. This article is protected by copyright. All rights reserved.
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